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A Review of Thyroid Dysfunction due to COVID-19

Category: Articles » A Review of Thyroid Dysfunction due to COVID-19

 

A Review of Thyroid Dysfunction due to COVID-19

 

Please click to this link: 

 

 

 

<Article link>

 

 

 

 

A Review of Thyroid Dysfunction due to COVID-19

 

Alireza Arefzadeh 1
Abstract

Coronavirus disease 2019 (COVID-19) affects thyroid function.

 

These changes are due to the direct impact of the virus on thyroid

 

 

cells via angiotensin-converting–enzyme 2 (ACE2) receptors,

 

 

inflammatory reaction, apoptosis in thyroid follicular cells,

 

 

suppression of hypothalamus-pituitary-thyroid axis,

 

 

an increase in activity of adrenocortical axis,

 

 

and excess cortisol release due to cytokine storm

 

 

of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

 

 

Euthyroid sick syndrome (ESS), thyroiditis, clinical and subclinical

 

 

hypothyroidism, central hypothyroidism, exacerbation of

 

 

underlying autoimmune thyroid disease, and clinical and

 

 

subclinical hyperthyroidism can be associated with coronavirus.

 

 

Adjuvants in coronavirus vaccines induce autoimmune/inflammatory syndrome

 

 

known as vaccine adjuvants (ASIA) syndrome.

 

 

Thyroiditis and Graves’ disease have been reported

 

 

to be associated with ASIA syndrome after some coronavirus

 

 

vaccinations. Some coronavirus medications, such as hydroxychloroquine,

 

 

monoclonal antibodies, lopinavir/ritonavir, remdesivir, naproxen,

 

 

anticoagulants, and glucocorticoids can also affect thyroid tests,

 

 

and correct diagnosis of thyroid disorders will be more difficult.

 

 

Conclusion: Changes in thyroid tests may be one of the most

 

 

important manifestations of COVID-19.

 

 

These changes can be confusing for clinicians and can lead to

 

 

inappropriate diagnoses and decisions.

 

 

Prospective studies should be conducted in the future to increase

 

 

epidemiological and clinical data and optimize the management

 

 

of thyroid dysfunctions in patients with COVID-19.

 

 

Keywords: Coronavirus disease 2019; severe acute

 

 

respiratory syndrome coronavirus 2; thyroid hormone;

 

 

thyroiditis; autoimmune disease; hyperthyroidism;

 

 

hypothyroidism; euthyroid sick syndrome; pandemic;

 

 

subclinical thyroiditis; painless thyrotoxicosis; thyroid dysfunction; thyrotoxicosis.

 

 

The author of the article:

 

 

Dr. Alireza Arefzadeh,

 

 

 

 

Endocrinologist

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

درمان چاقی شکم با آر اف درمان چاقی شکم چاقی شکم آر اف شکم آر اف کویتیشن اولتراسوند فوق تخصص غدد در تهران فوق تخصص غدد تهران بهترین فوق تخصص غدد تهران شمال جنوب شرق غرب بهترین فوق تخصص غدد در تهران بهترین فوق تخصص غدد تهران بهترین فوق تخصص غدد در شمال تهران بهترین فوق تخصص غدد در غرب تهران دکتر غدد در تهران بهترین دکتر متخصص غدد در تهران لیست پزشکان فوق تخصص غدد در تهران بهترین دکتر فوق تخصص غدد در تهران بهترین متخصص غدد در تهران متخصص غدد تهران بهترین متخصص غدد تهران متخصص غدد در تهران متخصص تیروئید تهران متخصص دیابت تهران متخصص تیروئید متخصص دیابت متخصص دیابت در تهران آدرس دکتر متخصص غدد در تهران آدرس دکتر فوق تخصص غدد در تهران متخصص تیروئید در تهران دکتر متخصص تیروئید در تهران بهترین فوق تخصص غدد تهران شمال جنوب شرق غرب متخصص داخلی دیابت تیروئید چاقی رشد بلوغ نازایی متخصص غدد خوب تهران دکتر متخصص غدد خوب در تهران دکتر متخصص دیابت در تهران دکتر متخصص تیروئید در تهران کلینیک فوق تخصصی غدد دکتر فوق تخصص غدد تیروئید کلینیک فوق تخصصی تیروئید دکتر متخصص غدد تیروئید دکتر متخصص غدد دیابت دکتر متخصص دیابت دکتر فوق تخصص غدد دیابت متخصص غدد تیروئید فوق تخصص غدد دیابت بهترین دکتر فوق تخصص غدد در تهران بهترین دکتر فوق تخصص تیروئید در تهران بهترین دکتر فوق تخصص دیابت در تهران بهترین دکتر متخصص رشد در تهران بهترین دکتر فوق تخصص رشد در تهران کلینیک فوق تخصصی دیابت کلینیک فوق تخصصی دیابت در تهران معرفی دکتر فوق تخصص غدد در تهران دکتر غدد خوب در تهران دکتر خوب غدد در تهران دکتر علیرضا عارف زاده فوق تخصص غدد دکتر علیرضا عارف زاده دکتر عارف زاده فوق تخصص غدد Dr alireza arefzadeh بهترین فوق تخصص غدد تهران شمال متخصص غدد شرق غرب جنوب فوق تخصص غدد بهترین فوق تخصص غدد بهترین فوق تخصص غدد تهران بهترین فوق تخصص غدد در تهران فوق تخصص غدد در تهران فوق تخصص غدد تهران فوق تخصص خوب غدد تهران فوق تخصص خوب غدد شمال تهران بهترین فوق تخصص غدد شرق تهران بهترین شمال تهران متخصص غدد بهترین متخصص غدد جنوب تهران بهترین متخصص غدد غرب تهران بهترین فوق تخصص غدد شمال تهران بهترین فوق تخصص غدد در شمال تهران متخصص غدد متخصص غدد تهران بهترین متخصص غدد تهران متخصص غدد در شمال تهران بهترین متخصص غدد در تهران فوق تخصص غدد در شمال تهران بهترین فوق تخصص غدد غرب تهران بهترین فوق تخصص غدد در غرب تهران بهترین فوق تخصص متخصص غدد شمال تهران دکتر غدد خوب در تهران دکتر خوب غدد در تهران دکتر علیرضا عارف زاده فوق تخصص غدد دکتر علیرضا عارف زاده Dr alireza arefzadeh

ا

 

 

 

Tags for this article: A Review of Thyroid Dysfunction due to COVID-19, Thyroid COVID-19, Thyroid, بهتزین دکتر تیروئید تهران, بهترین دکتر فوق تخصص تیروئید در تهران, بهترین فوق تخصص غدد در تهران, بهترین فوق تخصص غدد تهران

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Association of the Thyroid Nodules With FNA

Category: Articles » Association of the Thyroid Nodules With FNA

 

 

 

 

Association of the Thyroid Nodules With FNA

 

 

 

 

 

 

Please cick this link in below:

 

    

<Article Link>

 

 

 

 

 

 

 

Abstract

 

Thyroid nodules are a common finding in clinical practice.

 

Although ultrasonography is an accepted method for evaluating

 

 

these nodules, Fine Needle Aspiration (FNA) is the procedure of

 

 

choice for assessing the risk of malignancy. This study aims to determine

 

 

the association between sonographic features of thyroid nodules based on

 

 

Thyroid Imaging Reporting and Data System classification and the cytology results.

 

 

In this prospective cohort study, 147 patients from Tehran Medical Imaging Center

 

 

 

who had thyroid nodules underwent ultrasonography-guided FNA,

 

 

and their sonographic features were recorded.

 

 

The pathologic findings were also obtained according to the Bethesda system.

 

 

 

inally, the association between sonographic features and cytological results was

 

 

analyzed.

 

 

Eighteen (12.3%) nodules were malignant, and 129 nodules (87.7%) were benign. The

 

 

 

association of TIRADS categories with the risk of malignancy is as follows:

 

 

 

TIRADS 1 (n=0, 0%), TIRADS 2 (n=10, 16.9%), TIRADS 3 (n=6, 10.5%), TIRADS 4 (n=2, 16.7%), and TIRADS 5 (n=0, 0%).

 

 

 

 

The bloody lamellae of thyroid nodules were significantly correlated with

 

 

the risk of malignancy (P<0.05).

 

 

However, there was no statistically significant association between

 

 

the risk of malignancy and gender (P=0.47), calcification (P=0.9),

 

 

firmness (P=0.19), halo sign (P=0.95), location of nodules (P=0.35),

 

 

and nodules' echogenicity (P=0.058).

 

 

 

Although there are trusted classifications such as TIRADS for

 

 

categorizing thyroid nodules, there is still uncertainty in utilizing them,

 

 

especially in the management of nodules classified as TIRADS 2,

 

 

.

 

in which various sonographic features are shared between benign and malignant nodules.

 

 

Although, based on the ACR guideline, we do not perform FNA

 

with all nodules that have TIRADS 2, regardless of the size or other characteristics

 

of the nodule,

 

there is a possibility that some of these nodules will be malignant in the future,

 

 

so it is considered.

 

It seems that the guideline should be revised regarding TIRADS 2,

 

and under certain circumstances,

 

 

these types of nodules should also be sampled under FNA ultrasound guidance

 

with some criteria such as size or other features,

 

because there may be problems in the future,

 

contrary to what the guideline currently recommends,

 

that sampling TIRADS 2 is not required.

 

 be created and find out that some of these types of nodules are malignant 

 

Although currently, the ACR guideline does not recommend performing

 

thyroid nodule FNA with TIRADS 2

 

unless the patient has a positive family history of thyroid cancer,

 

 

. especially if family history is the MTC type or MEN.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Author and compiler:

 

Dr. Alireza Arefzadeh

 

 

 

 

 

 

 

 

endocrinology and metabolism specialist in Tehran

 

specialist in endocrine diseases in Tehran

 

 

the best endocrinologist in Tehran

 

the best endocrinologist in Tehran

 

the best subspecialist in Iran

 

the best endocrinologist in Iran

 

the best endocrinologist in Tehran

 

the best endocrinologist in Iran

 

the best specialist Thyroid in Tehran

 

FNA

 

thyroid ultrasound

 

 

 

 

 

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Evaluation of Ethanol Injection, Radiofrequency Ablation, and Levothyroxine Therapy in the Management of Benign Thyroid Nodules

Category: Articles » RF and Thyroid nodule

Evaluation of Ethanol Injection, Radiofrequency Ablation, and Levothyroxine Therapy in the Management of Benign Thyroid Nodules

 

                                                                                 

                                                                                         <Click here>

 

 

Abstract

Background:

Thyroid nodules are common clinical findings. Although there are various accepted treatments for benign thyroid nodules, such as surgery and thermal treatment, there are some alternative methods for the management of these patients at lower costs with minimal complications.

Objectives:

This study aimed to compare volume reduction in radiofrequency (RF) ablation and single-session ethanol ablation (EA) and to investigate the effects of levothyroxine therapy (LT4) on benign thyroid nodules.

Patients and Methods:

In this clinical trial, 91 patients with benign thyroid nodules, presenting to different medical centers in Tehran, Iran, from December 6, 2018, to December 6, 2019, were included. Patients who met the inclusion criteria were selected and randomly allocated into three groups: group 1, a single session of RF ablation (n = 31); group 2, a single session of ethanol injection (n = 30); and group 3, a six-month LT4 treatment (n = 30). Thyroid tests, including thyroid stimulating hormone (TSH), thyroxine (T4), triiodothyronine (T3), anti-thyroid peroxidase (anti-TPO), T3 resin uptake (T3RU), and serum calcitonin level, were recorded at baseline and within one-, three-, and six-month intervals. The nodule volume was also assessed using sonography at baseline and in the follow-ups.

Results:

The mean volume reduction was 73.6%, 80.1%, and 8.7% at six months after the intervention in the ethanol injection, RF ablation, and LT4 treatment groups, respectively (P < 0.001). There was a significant relationship between the mean volume reduction and the follow-up period (one, three, and six months) (P < 0.001).

Conclusion:

The RF ablation therapy was found to be the optimal modality for the management of benign thyroid nodules, as it was associated with the greatest mean volume reduction. Conversely, the lowest mean volume reduction was observed in the LT4 treatment group during six months of follow-up.
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Polycystic Ovary Syndrome

Category: Articles » Polycystic Ovary Syndrome

How to start a contraceptive in Patients with PCOS.

 

 

 

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CV (Resume)

Category: CV

Dr. Arefzadeh is Assistant Prof of Endocrinology and Metabolism.

 

Dr. Arefzadeh graduated from Tehran University of Medical Sciences in the field of Internal Medicine in 2008.

 

He graduated from Tehran University of Medical Sciences in the field of Endocrinology and Metabolism in 2012.

 

He has many researchs about internal medicine and endocrinology fields.

 

He is clinician and researcher and he works about diabetes mellitus, GDM, international education of diabetes and other endocrinology fields.

 

He likes teaching students, interns, residents and fellowships.

Dr. Arefzadeh has IELTS Document and he can speak three languages: English, Danish and Persian.

 

Dr. Arefzadeh has educated Iranians around the world regarding on the importance of Diabetes Mellitus and other metabolic disorders and has helped to resolve problems in the Iranian community.

 

He is member of American Diabetes Association(ADA) and European Society of Endocrinology(ESE) and European Research Association(CORDIS).

 

 

 

Tags for this article: Doctor arefzadeh alireza, Doctor alireza arefzadeh, alireza arefzadeh, Dr. alireza arefzadeh, Dr. Arefza, Dr. Alireza Arefzadeh, Dr. Arefzadeh, Tehran, Iran, Endocrinology, Metabolism, Endocrinologist, Internal Medicine, Physician

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FAQ from abroad

Category: FAQ from abroad

FAQ from abroad

 

 

 

Patients can contact me via my Email address: info@drarefzadeh.com

 

 

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Stress and Diabetes

Category: Patient Education » Stress and Diabetes

Stresss and Diabetes

 

 

 

Stress is the most important factor to predispose to diabetes.

 

Many diabetic patients have had a major stress before diabetes in my eperiences.

I have visited many diabetic patients who didn't  have positive diabetic family history,however, they have developed diabetes and they had major stress before diabetes.  

 

Stress can increase blood sugar and it can lead to bad habits like overeating, which can make diabetes harder to manage. 

Recerntly, some papers were published about this subject.

 

I strongly recommended to avoid stress and anxiety.

 

Dr. Alireza Arefzadeh.

Tags for this article: دکتر عارف زاده, دکتر عارف زاده علیرضا, دکتر علیرضا, دکتر عارف زاده علیرضا., دکتر علیرضا عارف زاده, Doctor arefzadeh alireza, Doctor alireza arefzadeh, alireza arefzadeh, تهران, ایران, فوق تخصص غدد, متخصص داخلی, متخصص غدد, Dr. alireza arefzadeh, Dr. Arefza

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News Media Technologies will create the revolution in education.

Category: Articles » Medical Education

News Media Technologies will create the revolution in education.

 

 

correspondent author:Alireza Arefzadeh

 

 

Abstract
Introduction:
News media, including content and methods for presenting it,
unmistakably contribute to the informal education of our students outside the
classroom. In addition to considering new media (television, video games, Internet,
etc.) as educative agents and keeping their influence in mind, educational institutions
incorporate these media into programs of study as content—including analysis of their
importance in society, function, and the repercussions, they may have in our lives.
Discussion:
News multimedia technologies must fulfill many basic functions:
- represent and present both real and virtual worlds.
- facilitate teaching.
- enhance student learning.
- improve IQ, residential, distance memory, and life-long learning.
- accommodate students’ learning styles.
- Digital Text Writing.
- Digital knowledge
- Connect people to teachers and Students and experts.
- Online courses registry.
-More Velocity and better quality Services.
-Immediately self Examination and scored, providing quick feedback.
With the arrival of computers, written textual language was first to be digitized
because it required the least amount of resources. The new Digital text can be
modified more easily, it can be sent from one place to another, words or strings of
characters can be searched for and found instantly, etc.
Social networking sites allow students to explore their interests on a global scale and
discuss their interests with a wider range of people. This has huge implications for
self-learning, as information and resources are much more available than they were
previously. However, for students that aren’t skilled at evaluating different content, it
can be hard for them to sort through various resources to find accurate and useful
information. Important Social networking sites are
Twitter,Wikipedia,Google,Yahoo, Facebook, and Youtube, Smartphones and
Iphone. Educational institutions will successfully wed academia and technology,
allowing students to learn in new and innovative ways. Technology has great potential
to help people learn, and businesses should capitalize on the advantages of technology
to create technologically advanced educational systems. They change to accommodate
students’ learning styles and significantly change education of the future. The Internet
allows people to search through digital knowledge and connect people to teachers and
experts. Textbooks can become interactive and can easily include updates and
corrections. Students will likely be able to get coursework from whichever university
they choose, and courses will likely be collaborative and public. These changes will
allow universities to teach anyone willing to learn, rather than only a select few in a
classroom. Technologies are already changing education, as online schools allow
students to earn degrees through only online courses Computer-Based Trainings are
self-paced activities on a computer that present content to a user. The trainings often
include assessments that can be immediately scored, providing quick feedback to the
users.
Conclusion: News Media Technologies provide revolution in education.

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Accuracy of three imaging modalities for evaluation of the posterior lens capsule in traumatic cataract

Category: Articles » Others

Accuracy of 3 imaging modalities for evaluation of the posterior lens capsule in traumatic cataract

 

Click below link:

 

Accuracy of three imaging modalities for evaluation of the posterior lens capsule in traumatic cataract

 

 

 

Accuracy of 3 imaging modalities for evaluation of the posterior lens capsule in traumatic cataract.

Abstract

PURPOSE:

To compare the accuracy of 3 imaging modalities for preoperative evaluation of the posterior lens capsule in traumatic cataract.

SETTING:

Farabi Eye Hospital, Tehran, Iran.

DESIGN:

Case series.

METHODS:

The study comprised eyes with traumatic cataract opaque enough to prevent visualization of the posterior lens capsule on slitlamp examination. To detect posterior lens capsule rupture before surgery, imaging was performed with 20 MHz echography (Eye Cubed), anterior segment optical coherence tomography (AS-OCT) (Visante model 1000), and Scheimpflug imaging (Pentacam). All patients subsequently had cataract extraction, and the intraoperative findings of the posterior lens capsule were compared with the preoperative findings of the imaging modalities.

RESULTS:

The study enrolled 21 eyes of 21 patients (20 men, 1 woman) with a mean age of 31.5 years ± 1.45 (SD). The nature of trauma was blunt (5 eyes) or sharp (16 eyes). To detect posterior lens capsule rupture, the sensitivity and specificity were, respectively, 80% and 86% for 20 MHz echography, 71% and 77% for AS-OCT, and 62% and 57% for Scheimpflug imaging (95% confidence intervals: sensitivity, 30.00-90.32; specificity, 54.81-92.95). Insufficient resolution for posterior lens capsule evaluation occurred in 33.3% cases for AS-OCT and 57.1% cases for Scheimpflug imaging. The accuracy of 20 MHz echography, AS-OCT, and Scheimpflug imaging was 76.1%, 61.9%, and 42.9%, respectively.

CONCLUSION:

In the evaluation of the posterior lens capsule in eyes with traumatic cataract, 20 MHz echography had higher accuracy than AS-OCT and Scheimpflug imaging.

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High prevalence sleep disordered breathing in patients with diabetic macular edema

Category: Articles » Diabetes Retinopathy

High prevalence sleep disordered breathing in patients with diabetic macular edema (1)

 

High prevalence sleep disordered breathing in patients with diabetic macular edema

 

Arefzadeh A, MD.

Endocrinology department; Imam Hospital; Tehran University of Medical Sciences; Tehran; Iran

 

Correspondent author: Arefzadeh Alireza

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About Us :

Dr. Alireza Arefzadeh
Assistant Prof of Endocrinology & Metabolism
Faculty Member of Medical University
Internal Medicine Specialist
Endocrinology and Metabolism SubSpecialist
Clinician and Researcher
Member of American Diabetes Association(ADA).
Member of European Society of Endocrinology(ESE)and European Research Association(CORDIS).

Contact Us :

Address :Norrebrogade, Copenhagen N, 2200 Denmark.
Phone :004591731837
E-mail :info@drarefzadeh.com
Contact TEL Number for patients outside Iran: 0016612623255-0037253141799-00447700309990
Contact TEL Number for patients inside Iran: 02122898836-09198673034-09373622621
آدرس: تهران، خیابان شریعتی، بالاتر از میرداماد، روبروی مترو شریعتی، جنب پمپ بنزین شریعتی(مینا)، کوچه شواری، پلاک 29، ساختمان پزشکان سینا، طبقه4، واحد 16. روزهای زوج از ساعت 5بعداز ظهر تا 7 شب تلفن تماس:09198673034-02122898836 تلفن پاسخ گویی به سوالات09373622621
 

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